Covid-19 Defense

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Covid-19 Defense
  
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WHAT YOU NEED TO KNOW 
  • If everyone's system had the optimum amount of vitamin D, selenium and vitamin C the COVID-19 virus would not be the issue that it is today.

  • Vitamin D is actually a hormone rather than a vitamin. The liver and kidneys convert vitamin D (produced in the skin and taken up in the diet), into the active hormone, which is called calcitriol.

  • Chinese are notoriously deficient in vitamin D and selenium, as are Americans, especially Black Americans.  COVID-19 started in China as did many other viral outbreaks. Viruses easily infect and become more virulent in individuals that are deficient in vitamin D or selenium.

  • individuals with underlying conditions are more likely to be vitamin D deficient because of their bodys increased need of the vitamin.

Below is a reprint of a recently published article on COVID-19 and Vitamin D.
Review. 2020 Apr 2;12(4):988. doi: 10.3390/nu12040988.
Evidence That Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
William B Grant1, Henry Lahore2, Sharon L McDonnell3, Carole A Baggerly3, Christine B French3, Jennifer L Aliano3, Harjit P Bhattoa4
Affiliations
1. Sunlight, Nutrition, and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603, USA. 
2. 2289 Highland Loop, Port Townsend, WA 98368, USA.
3. GrassrootsHealth, Encinitas, CA 92024, USA.
4. Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei Blvd 98, H-4032 Debrecen, Hungary.
PMID: 32252338 PMCID: PMC7231123 DOI: 10.3390/nu12040988
Free PMC article
Abstract

The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed. This article reviews the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk. Through several mechanisms, vitamin D can reduce risk of infections. Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines. Several observational studies and clinical trials reported that vitamin D supplementation reduced the risk of influenza, whereas others did not. Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D (25(OH)D) concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity, both of which are associated with lower 25(OH)D concentration. To reduce the risk of infection, it is recommended that people at risk of influenza and/or COVID-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40-60 ng/mL (100-150 nmol/L). For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations.
 
Keywords: COVID-19; UVB; acute respiratory distress syndrome (ARDS); ascorbic acid; cathelicidin; coronavirus; cytokine storm; influenza; observational; pneumonia; prevention; respiratory tract infection; solar radiation; treatment; vitamin C; vitamin D.
Conflict of interest statement
W.B.G receives funding from Bio-Tech Pharmacal, Inc. (Fayetteville, AR). H.L. sells vitamin D supplements. GrassrootsHealth works with various supplement suppliers to test the efficacy of their products in various custom projects. These suppliers may be listed as sponsors of GrassrootsHealth. H.P.B. has no conflicts of interest to declare.
 
 
 Vitamin D has long provided significant support for healthy bone density. However, scientists have also validated the critical role that vitamin D plays in regulating healthy cell division and differentiation, and its profound effects on human immunity. These findings link a deficiency of vitamin D to a host of common age-related problems.
 Selenium is an essential micronutrient for human health. In the body, it is incorporated into enzymes and other proteins to make vital compounds known as selenoproteins. Se-Methyl L-Selenocysteine (MSeC) is an organic selenium compound that is more absorbable than inorganic selenium salts typically used in supplements. Perhaps the best-known selenoprotein is the antioxidant enzyme glutathione peroxidase. Each molecule of glutathione peroxidase requires four selenocysteine units and catalyzes a reaction in which a free radical is scavenged by glutathione.
Restore youthful immune function

Senolytic Activator 
 
Senolytic ActivatorOur NEW Senolytic Activator combines black tea theaflavins with an ultra-absorbable form of quercetin to help manage senescent cell burden and promote systemic rejuvenation. Fight back against cellular senescence with Senolytic Activator!

Benefits at a Glance:

  • Helps the body manage senescent cells
  • Promotes youthful, healthy cellular function
  • Delivers an ultra-absorbable form of quercetin
  • Supports systemic rejuvenation
  • take only once per week
More facts about Senolytic Activator

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.

Senolytic compounds selectively target senescent cells. New research indicates that black tea theaflavins and quercetin target specific biological pathways, making it easier for the body to manage senescent cells.

Immune Senescence Protection Formula™
 
Restore youthful immune function
Think of your immune cells as bouncers at a night club. They control who gets in, who gets kicked out and who can’t enter ever again. But over time, our immune system begins to decline, a process called immune senescence. This makes it harder for immune cells to do their job. So we developed an innovative formula to help combat immune senescence.

Immune cells are like security guards. They say who’s in, who’s out and who’s banned. However, our immune system declines over time.

Immune Senescence Protection Formula™ Benefits
· Inhibits immune senescence by supporting an already-healthy ratio of naïve-to-memory T cells
· Promotes youthful immune response by stimulating immune cell development and activity
· Encourages the body’s first line of defense by promoting natural killer (NK) cell response
· Supports bone marrow health and longevity
Bio-Quercetin
 
Quercetin: A Plant-Based Senolytic

Quercetin, a compound found in many fruits and vegetables, has long been recognized for its health benefits. It is an anti-inflammatory agent that has been shown to protect cells and tissues from injury.

In lab studies, quercetin has been demonstrated to improve markers of aging and extend lifespan. Human studies have shown quercetin reduces or prevents age-related disease and dysfunction.

In addition to these general health and longevity promoting benefits, the medical literature supporting quercetin as a senolytic has been growing over the last decade.

Quercetin, when combined with other compounds, can clear senescent cells from tissues. When applied directly, quercetin may enable a rejuvenating effect in healthy cells.
Theaflavin Standardized Extract
 
Theaflavin: A Black Tea Based Senolytic

Theaflavins are unique compounds present in black tea.

Based on published studies, researchers discovered that theaflavins, found in black tea, target some of the same cellular signaling pathways as dasatinib and other senolytic drugs known as BCL-2 inhibitors.

Signaling pathways comprise the cellular communication network. These signals are passed from molecule to molecule in the cell, giving the cell instructions on what to do. When signaling pathways become distorted it can result in cancer, senescence, or other diseases.

Theaflavins may act as a senolytic agent by inhibiting cellular receptors Eph, BRC-ABL, and BLC-2 to clear senescent cells from the body. Therefore, without the side effect concerns about drugs that many may have, it is possible to create a senolytic cocktail using both theaflavins and quercetin to target signaling pathways to remove useless senescent cells.
  
This page talks of the most effective ways to remove senescent cell from your body.