Irvingia
induce fat-loss via four different mechanisms:
- It up-regulates the expression of adiponectin,
thereby improving insulin sensitivity.
- It is associated with lower levels of C-reactive
protein and helps restore the dual weight control
effects of leptin.
- It inhibits glycerol-3-phosphate dehydrogenase,
thereby reducing fatty acid formation in the body
and inhibiting the amount of blood glucose that
converts to fat.
- It inhibits the enzyme amylase, thus reducing
the amount of ingested starches that will be
absorbed as sugar.
Read
article about Irvingia
Scientists have identified specific
biological mechanisms that cause aging people to gain
weight… no matter how little they eat. The problem was
that there was no way to circumvent the underlying
factors that cause excess body fat… until now! As you
are about to learn, gaining control over your body’s
command signals is critical to maintaining a healthy
weight.
Leptin is a hormone that tells our
brain that we have consumed enough calories and can stop
eating. Leptin also induces a process whereby fat stored
in cells is broken down. As we age, our cells (including
the appetite control center in our brains) become “leptin
resistant.” This means that leptin is unable to
effectively regulate body weight.
Adult-onset weight gain is
characterized by the enlargement of existing adipocytes
(fat cells) that store too much fat. The size of fat
cells is controlled by gene transcription factors. Fat
cell size is closely related with adiponectin expression
— with reduced adiponectin expression in larger fat
cells. In addition, gene transcription factors help
regulate adiponectin, and this crucial hormone is
critical for supporting insulin sensitivity.
An enzyme called
glycerol-3-phosphatedehydrogenase is critical for
synthesizing fatty acids in our bodies. Suppressing this
enzyme helps reduce the amount of glucose (sugar) in our
bloodstream from being converted into fatty acids.
Irvingia and
Weight Loss Supplements
Weight loss
utilizing diet modification, supplements, hormones or
drugs usually functions via a single mechanism.
Adipocytes (fat cells), on the other hand, possess
numerous means to ensure their survival. An extract from
a West African plant called
Irvingia
has been shown to help maintain healthy body weight in
four ways:*
Weight Management: Reversing Leptin
Resistance
Fat cells
produce C-reactive protein, a pro-inflammatory compound
that leads to “leptin resistance.” Overweight people
given Irvingia have lower levels of CRP, and therefore
less CRP is able to block the activity of leptin. Leptin
is important in
weight management
because it promotes the breakdown of fat in adipocytes
and tells the brain to turn off chronic hunger messages.
Hormones: Increasing Adiponectin
Large fat cells secrete less
adiponectin, and adiponectin is a crucial hormone that
helps support insulin sensitivity as well as
cardiovascular health. Overweight people given Irvingia
show markedly increased adiponectin levels.
Weight Loss: Inhibiting the Fat
Converting Enzyme
An enzyme called glycerol-3-phosphate
dehydrogenase facilitates the conversion of glucose into
triglycerides that increase adipocyte size. Irvingia
inhibits glycerol-3-phosphate dehydrogenase, thus
reducing the amount of glucose (sugar) that is converted
to fat in the body.
Diet: Reducing Carbohydrate
Absorption
In order for carbohydrates to be
fully absorbed, they must be broken down in the
digestive tract by the amylase enzyme. Irvingia inhibits
amylase, and thus reduces the amount of ingested
starches that will be absorbed as sugar.
Several studies demonstrate the
weight loss
properties of Irvingia.1
In the largest placebo controlled human study, those
taking Irvingia lost 28 pounds over a 10-week period
compared to only up to 3 pounds in the placebo group.2
The study participants did not alter their diet.*
Based on
impressive human data, a dose of 150 mg of Integra-Lean™
Irvingia
taken twice a day is all that was needed to achieve
unprecedented clinical results.
This supplement should be taken in
conjunction with a healthy diet and regular exercise
program. Results may vary.
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