Senolytics

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A New Paradigm in Health and Rejuvenation
  
Energetic older couple enjoying life
Energetic  older couple enjoying life
WHAT YOU NEED TO KNOW 
  
Senolytics:
·  Supports systemic rejuvenation
·
  Promotes youthful, healthy cellular function
·
  Improve frailty symptoms (gait, grip strength)
·
  Enhance hair color appearance

·  Improve cardiac/arterial function
·  Reduce tremors and urinary incontinence
·  Decrease osteoporosis
·  Increase exercise endurance
·  Improve kidney/liver age scores
·  Extend healthy lifespan
Removal of Senescent Cells “Might Transform Medicine”
Researchers at the Mayo Clinic have pinpointed a major cause of aging and a cause of many of the diseases of aging. And have identified a simple way to remove it.

When cells stop dividing and become dysfunctional they are supposed to go through a process of self-elimination called apoptosis (programmed cell death). Sometimes the apoptosis pathway becomes blocked and the cell doesn't die.  It lingers in a zombie like state emitting protein-degrading enzymes that wreak havoc upon healthy cells. If only one cell in 7,000 to 15,000 cells become senescent, that one cell will  initiate degenerative aging.

These senescent cells accumulate over time, causing systemic age deterioration while they accumulate into the millions. Senescent cells are in all of our tissues.

Senescent  immune  cells  is the reason why the elderly die of pneumonia, colds, influenza and other common diseases.
The immune system become clogged with non-functional immune cells and thereby become dysfunctional.

There is a class of compounds call "senolytics" that can remove senescent cells from our bodies.

Senolytics should be part of everyone's recovery.  Recovery cannot be complete until senescent cells are removed from our bodies.

Read the two articles below for a better idea of the importance of senolytics.
   
1. A Biomedical Renaissance: Removal of Senescent Cells “Might Transform Medicine”
2. Major Advance in Healthy Longevity: Senolytics
COMBAT Senescent Cells and AGING

Senolytic Activator 
 
Senolytic Activator Our NEW Senolytic Activator combines black tea theaflavins with an ultra-absorbable form of quercetin to help manage senescent cell burden and promote systemic rejuvenation. Fight back against cellular senescence with Senolytic Activator!

Benefits at a Glance:

  • Helps the body manage senescent cells
  • Promotes youthful, healthy cellular function
  • Delivers an ultra-absorbable form of quercetin
  • Supports systemic rejuvenation
  • take only once per week
More facts about Senolytic Activator

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.

Senolytic compounds selectively target senescent cells. New research indicates that black tea theaflavins and quercetin target specific biological pathways, making it easier for the body to manage senescent cells.

Theaflavin Standardized Extract
 
Theaflavin Standardized Extract Theaflavin: A Black Tea Based Senolytic

Theaflavins are unique compounds present in black tea.

Based on published studies, researchers discovered that theaflavins, found in black tea, target some of the same cellular signaling pathways as dasatinib and other senolytic drugs known as BCL-2 inhibitors.

Signaling pathways comprise the cellular communication network. These signals are passed from molecule to molecule in the cell, giving the cell instructions on what to do. When signaling pathways become distorted it can result in cancer, senescence, or other diseases.

Theaflavins may act as a senolytic agent by inhibiting cellular receptors Eph, BRC-ABL, and BLC-2 to clear senescent cells from the body. Therefore, without the side effect concerns about drugs that many readers of this magazine have, it is possible to create a senolytic cocktail using both theaflavins and quercetin to target signaling pathways to remove useless senescent cells.
   
   
Bio-Quercetin
 
Bio-Quercetin Quercetin: A Plant-Based Senolytic

Quercetin, a compound found in many fruits and vegetables, has long been recognized for its health benefits. It is an anti-inflammatory agent that has been shown to protect cells and tissues from injury.

In lab studies, quercetin has been demonstrated to improve markers of aging and extend lifespan. Human studies have shown quercetin reduces or prevents age-related disease and dysfunction.

In addition to these general health and longevity promoting benefits, the medical literature supporting quercetin as a senolytic has been growing over the last decade.

Quercetin, when combined with other compounds, can clear senescent cells from tissues. When applied directly, quercetin may enable a rejuvenating effect in healthy cells.
 
 
   
  
This page talks of the most effective ways to remove senescent cell from your body.