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The mitochondria are the cells’
energy powerhouses, and coenzyme Q10 (CoQ10) is an
essential component of healthy mitochondrial function.
CoQ10 is required to convert the energy from fats and
sugars into usable cellular energy. Yet, the body’s
production of CoQ10 declines significantly with
advancing age. With an ample amount of CoQ10,
mitochondria can work most efficiently throughout the
entire body—including the most densely populated area,
the heart. CoQ10 is also a
potent antioxidant, helping protect proteins, and DNA of
mitochondria from oxidation and supporting mitochondrial
function.
More people are supplementing
with CoQ10 than ever before. One reason is increased
awareness that “statin” drugs used to lower LDL and
cholesterol deplete CoQ10 levels in the blood, and
possibly the tissues.
What most doctors don’t know,
however, is that normal aging may result in more of a
reduction in CoQ10 than taking statins. For example,
while statin drugs have been shown to reduce plasma
CoQ10 by 40%, the aging process reduces CoQ10 levels in
the heart muscle wall by 72%.
What is particularly frightening is the deficit caused
by the dual effects of aging
and statin drug use that can result in severe depletion
of cellular vitality.
CoQ10 is notoriously difficult to
absorb. When it comes to choosing a CoQ10 supplement,
the primary factor is how many swallowed milligrams
actually make it into your bloodstream. A recent study
showed that in seriously ill patients, conventional
ubiquinone CoQ10 was hardly detectable in the blood
whereas ubiquinol resulted in significant blood level
increases and subsequent clinical improvements.
Scientific studies show that ubiquinol absorbs up to 8
times greater than ubiquinone, and higher levels of
ubiquinol remain in the blood far longer than ubiquinone.
In studies measuring exercise-induced fatigue,
ubiquinol
was 90% more effective than ubiquinone. In middle-aged
mice, ubiquinol was shown to be 40% more effective in
slowing measurements of aging compared to ubiquinone.
Life Extension offers the highly bioavailable
ubiquinol
form of CoQ10 in a patented delivery system with a
superior absorption level.
This formulation contains an
organic compound called PrimaVie® shilajit that research
shows doubles levels of CoQ10 in mitochondria.
Shilajit has
been shown to help restore and sustain
cellular energy.
The latest studies reveal that when shilajit is combined
with CoQ10, cellular energy gains substantially
increase.
In a breakthrough preliminary
study, the combination of CoQ10 and shilajit produced a
56% increase in cellular energy production in the brain
— 40% better than CoQ10 alone. In muscle there was a
144% increase, or 27% better than CoQ10 alone.
Researchers have found that shilajit
works to boost CoQ10’s beneficial effects by:
- Stabilizing CoQ10 in its
superior ubiquinol form, thereby prolonging its
action at the cellular level.
- Facilitating more
efficient delivery of CoQ10 into the mitochondria,
resulting in greater cellular energy output.
Scientific analysis shows that
shilajit itself is rich in essential compounds that
promote mitochondrial metabolism. Part of shilajit’s
beneficial effects derive from its ability to help the
mitochondria convert fats and sugars into adenosine
triphosphate, or ATP, the main source of cellular
energy. Super Ubiquinol CoQ10 with Enhanced
Mitochondrial Support™ combines super absorbable
ubiquinol CoQ10 with shilajit to generate a powerful
synergy that supports more youthful cellular energy
production than CoQ10 alone.
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